In mammals, the central pacemaker suprachiasmatic nuclei (SCN) in the hypothalamus synchronises peripheral clocks in most major body organs. The circadian clocks are internal timing mechanisms which drive ∼24-hour rhythms in physiology and behaviour. Hill Building, Oxford Road, Manchester M13 9PT, UK .uk
5 NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, Manchester, UKĭr Qing-Jun Meng, Faculty of Life Sciences, University of Manchester, A.V. 4 Faculty of Medical and Human Sciences, Centre for Tissue Injury and Repair, University of Manchester, Manchester, UK. 3 Murdoch Children's Research Institute, Parkville, Victoria, Australia. 2 Wellcome Trust Centre for Cell Matrix Research, University of Manchester, Manchester, UK. 1 Faculty of Life Sciences, University of Manchester, Manchester, UK.
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